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מחקרים

 

מחקרים בנושא חומצה היילורונית, יתרונותיה והשפעותיה בטיפול במחלות חניכיים שפורסמו ע״י המגזינים המובילים בתחום הרפואה הדנטלית ובוצעו ע״י מומחים בינלאומיים לרפואת חניכיים .

את המחקרים ניתן לקרוא ולהוריד בפורמט PDF.

The role of Hyaluronic Acid in managing inflammation of periodontal disease

By Peter N. Galgut

״gingivitis and periodontitis are an inflammatory condition of the oral cavity. They are charecterising by bleeding, redness and tissue break down around .."

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Hyaluronic Acid as an adjunct after scaling and root planing: a prospective randomized clinical trial.

Journal of Periodontology; Copyright 2012

By Eick S1, Renatus A, Heinicke M, Pfister W, Stratul SI, Jentsch H

״The study is designed to determine the effect on clinical variables, subgingival bacteria, and local immune response brought about by application of hyaluronan .."

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The efficacy of topical H.A Hyaluronic Acid in the management of recurrent aphthous ulceration


J Oral Pathol Med (2006)

By A. Nolan, C. Baillie, J. Badminton, M. Rudralingham, R. A. Seymour

״Topical preparations appear to be the main agents
used in the treatments of RAU, especially those with an antiinflammatory action.."

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Local application of Hyaluronan gel in conjunction with periodontal surgery_a randomized controlled trial


Clin Oral Invest (2011)

By Karim M. Fawzy El-Sayed, Moushira A. Dahaba, Shadw Abul-Ela, Mona S. Darhous

״Hyaluronic acid application has been proven to be beneñcial in a number of medical disciplines. The aim of the current..."

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Treatment of gingivitis with Hyaluronan


Journal of Clinical Periodontology (2003)

By Jentsch H1, Pomowski R, Kundt G, Göcke R.

״Hyaluronic acid (hyaluronan) is a glycosaminoglycan
with anti-inflammatory and antiedematous properties.
It was evaluated in a gel formulation for its effect in the treatment of plaque-induced gingivitis."

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Modern management of periodontal diseases
March / April 2015

By Peter N. Galgut

"The UK adult health survey (1998) has shown that approximately half of the adult population of England and Wales have moderate periodontal disease .."

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Evaluation of hyaluronan gel (Gengigel) as a topical applicant in the treatment of gingivitis
Journal of Investigative and Clinical Dentistry (2011)

By Nadiger Sapna & Kharidi Laxman Vandana

״Aim: To clinically and histopathologically evaluate the
anti-inflammatory effect of0.2% hyaluronan gel alone and with mechanical therapy on gingivitis.."

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Peri-implant maintenance of immediate function implants: a pilot study comparing hyaluronic...
Int J Dent Hygiene  (May, 2007)

By M de Arau´jo Nobre, N Cintra, P Malo´

״Introduction: In implants, maintenance assumes animportant role. The role of chlorhexidine (CHX) is well knownin maintenance, while only limited .."

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Local Delivery of Hyaluronan as an adjunct to scaling and root planning in the treatment of chronic periodontitis


J Periodontol  (2009)

By Annsofi Johannsen, Monica Tellefsen, Ulf Wikesjo, Gunnar Johannsen†

״The aim of the present study was to evaluate

the adjunctive effect of the local application of ..."

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Hyaluronan in morphogenesis and remodeling


Glycoforum (1998)

By Bryan P. Toole

״Almost everything about hyaluronan is unusual; yet its extraordinary attributes derive from a chemical composition that is very simple. Hyaluronan is a uniformly repetitive.."

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Evaluation of Hyaluronate anti-ulcer activity against gastric mucosal injury


African Journal of Pharmacy and Pharmacology (2011)

By Fouad Al-Bayaty, Mahamood Abdulla and Poya Darwish

" The present study was performed to evaluate the anti-ulcerogenic activity of hyaluronic acid against ethanol induced gastric mucosal injury in rats."

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Bacteriostatic Effects of Hyaluronic Acid


J Periodontol (1999)

By Payman Pirnazar, Larry Wolinsky, Sushma Nachnani, Susan Haake, Andrea Pilloni, and George W. Bernard

״ This investigation is one of a series of projects seeking
to ascertain whether hyaluronic 
acid (HA) is the
rapeutically effective in tissue 
regeneration procedures.."

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Action of Hyaluronan Acid on the wound healing process following extraction


Dental Information No 2 (2004)

By Eric Baisse1, Bernard Piotrowski1, Philippe Piantoni2, Gérard B...

" Hyaluronic acid (HA) is a glycosaminoglycan of the general formula (C14H22NO11)n. It is an essential component of the extracellular matrix in connective tissue .."

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Expression of proteoglycans and Hyaluronan during wound healing


The Journal of Histochemistry And Cytochemistry (1995)

By Oksala O1, Salo T, Tammi R, Häkkinen L, Jalkanen M, Inki P..

" We investigated the expression of proteoglycans (PGs) and hyaluronan (HA) during healing of human mucosal wounds. Biopsy specimens of experimental .. "

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A comparison in postoperative healing of sites receiving non-surgical debridement augmented with and without a single application of hyaluronan 0.8%

 

Preventive Dentistry vol 2 (2007)

By Koshal, Amit: BDS (HONS) MFGDP (UK) MFDS RCS (ENG) Patel...

" Chronic Adult Periodontitis affects over 2/3 of all patients in the UK aged greater than 45 years.."

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The antioxidant and anti-inflammatory efficiency of hyaluronic acid after third molar extraction

 

Journal of Cranio-Maxillo-Facial Surgery  (2015)

Gokhan Gocmen a, Onur Gonul a, Nihal Sehkar Oktay b, ...

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" Hyaluronic acid (HA) has a number of clinical applications in current practice. Therefore, cor- relation of HA with free radicals and inflammatory cells .."

Topical hyaluronic acid in the management of oral ulcers


Indian Journal of Dermatology (2011)

By Pranav Kapoor, Shabina Sachdeva, Silonie Sachdeva

" This article reviews the mechanism of action, indications and efficacy of topical Hyaluronic acid gel in the .."

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Guided bone regeneration by poly(lactic-co-glycolic acid) grafted hyaluronic acid bi-layer films for periodontal barrier applications

 

J.K. Park et al. / Acta Biomaterialia 5 (2009)

By Jung Kyu Park a, Junseok Yeom a, Eun Ju Oh a, Mallikarjuna ...

" A novel protocol for the synthesis of biocompatible and degradation controlled poly(lactic-co-glycolic acid) .."

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The efficacy of topical 0.2% hyaluronic acid gel on recurrent oral ulcers: comparison between recurrent aphthous ulcers and the oral ulcers of Behçet’s disease

 

JEADV (2008)

By JH Lee, JY Jung, D Bang

" Thirty-three outpatients with recurrent oral ulcers were.."

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Salivary levels of hyaluronic acid in female patients with dry mouth compared with age-matched controls: a pilot study

 

Biomed Res. (2009)

By Higuchi Y1, Ansai T, Awano S, Soh I, Yoshida A, Hamasaki T ...

" Little is known regarding the association between the level of hyaluronic acid (HA) in saliva and dry mouth status .."

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A SINGLE SITE, OPEN NON-
CONTROLLED STUDY OF EFFICACY AND TOLERABILITY OF TWO FORMULATIONS
OF THE MEDICAL DEVICE GENGIGEL ® BABY GEL (0.2% HYALURONIC ACID) IN
THE TOPICAL TREATMENT OF TEETHING IN INFANTS

By PHD student at University of Medicine and Pharmacy “Victor  ...

" Health promotion is the process of enabling people to increase control over, and to improve, their health .."

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Potential role of high molecular weight hyaluronan in the anti-Candida activity of human oral epithelial cells

 

Medical Mycology (2007)

By AKIYOSHI SAKAI, SUMIO AKIFUSA, NAOKI ITANO, KOJI KIMATA...

" Candida albicans is both a commensal and a pathogen in the oral mucosa. Previous studies have indicated that epithelial .."

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Clinical evaluation of demineralized bone allograft in a hyaluronic acid carrier for sinus lift augmentation in humans: a computed tomography and histomorphometric study

 

Oral Impl. Res. 18 (2007)

By Zvi Schwartz, Moshe Goldstein, Einav Raviv, Ariel Hirsch...

" Natural and synthetic graft materials are used routinely in sinus floor augmentations to help support implants in atrophic maxillary ridges .."

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Evaluation of Safety of Use of Gingival Gel Based on Hyaluronan in Two Formulation With Different Flavours 

 

Ricerfarma (2003)

By Prof Paolo Pigatto, Dr. Gianpaolo Guzzi

" Materials tested : Gengigel Baby, Gengigel Junior . On request by Riservice Srl, a trial was conducted on a group of 40 males and females volunteers aged 5-14  .."

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Hyaluronic acid stimulates neovascularization during the regeneration of bone marrow after ablation

 

WILEY PERIODICALS, INC. (2011)

By Andrew L. Raines, MoonHae Sunwoo, Arthur A. Gertzman...

" Restoration of vasculature is a critical component for successful integration of implants in musculoskeletal tissue. Sodium hyaluronate (NaHY) has been used as a carrier .."

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By P Malo

"המחקר עוסק בשתלים עם העמסה מיידית All On Four . כשמדובר על הצלחה של קליטת שתלים - להגיינה האוראלית של המתרפאים יש השפעה משמעותית על יציבות העצם   .."

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השוואה בין שימוש בחומצה היאלורונית מול כלורוקסידין
לאחר השתלה

(2007) Int Dent Hygiene 5 
 

Proteoglycans at the bone-implant interface

 

Crit Rev Oral Biol Med. (1998)

By Klinger MM1, Rahemtulla F, Prince CW, Lucas LC, Lemons JE

" The widespread success of clinical implantology stems from bone's ability to form rigid, load-bearing connections to titanium and certain bioactive coatings. Adhesive biomolecules in the .."

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